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Ambien: a pill that solves sleep disorders
|Drug Name:||Ambien Zolpidem|
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Without a good night’s sleep, it is challenging to stay active and alert during the day. When the problem persists, the quality of life drops and other health issues may also arise. No wonder, so many people look for the proper treatment of sleep disorders.
It must be prescribed by the doctor and nowadays often includes such a medicine as Ambien. Let’s discover more information about this drug and its features.
The mechanism of action and the main action of Ambien
Ambien is a brand name for the medicine that contains Zolpidem as an active ingredient. This compound belongs to the group of medicines called benzodiazepines. Among them, there are many powerful tranquilizers and anticonvulsants, as well as drugs for the treatment of sleep disorders.
Thus, Ambien selectively binds a special place in GABA receptors and provokes a strong hypnotic effect together with light anticonvulsant, anxiolytic and myorelaxant activity. GABA stands for gamma-aminobutyric acid. This compound is a natural inhibitor in the central nervous system that the brain emits to calm down its cells. If its concentration is insufficient or the production is disturbed, such medicines as Ambien are prescribed to solve the problem.
Thus, Ambien’s main indication for the usage is insomnia. The medicine improves sleep onset or the time one requires to fall asleep. In addition, it prolongs the duration of sleep. The treatment usually lasts from two to six weeks and starts from the lowest possible doses. Moreover, medicinal treatment is recommended only if all other measures, such as sleep hygiene and behavioral therapy, have been tried without success.
This is because of a quite powerful effect of the medicine and the possible side effects associated with it. The patient can easily become tolerant to it. Moreover, an abrupt withdrawal may cause seizures and other life-threatening side effects, so this type of treatment must be done only under the doctor’s control.
List of contraindications
The main contraindications for this medicine include:
- obstructive sleep apnea;
- liver issues;
- respiratory depression;
- psychotic diseases.
It is prescribed with caution for people who were addicted to alcohol or drugs. In addition, there was a recommendation to decrease the dosage for women, as they are more susceptible to possible side effects of the medicine.
The utilization of Ambien is prohibited for children and women during pregnancy and breastfeeding. Certain scientific investigations on mice revealed harmful effects on the fetus’s development. Elderly patients should also avoid this medicine due to possible harmful cognitive effects.
Possible side effects and precautions
Usually, Ambien provides good efficiency combined with only a few side effects. They are reported by less than 7% of the patients and include:
- drowsiness and dizziness;
Long-term utilization is sometimes associated with sinusitis, back pain, dry mouth, sore throat, lightheadedness, skin rash and amnesia. It should be noted that the intake of this medicine increases the probability of depression, falls with bone fractures and suppressed respiration.
In addition, a so-called hangover effect sometimes occurs during the next day after the intake of the medicine. In this case, a patient feels unusual sleepiness and his or her psychomotor and cognitive functions are disturbed. This may be the reason for falls and bone fractures. Moreover, it makes driving a vehicle more than dangerous.
That is why it is recommended to follow the condition of the patient during the first week of the intake and check whether or not this effect occurs.
Furthermore, Ambien must not be combined with other medicines or substances that inhibit the activity of the central nervous system because such a combination may lead to coma and even death. Thus, alcohol is fully prohibited during the treatment.
The course is usually started from the lowest dosage of 5 mg. Then, it can be increased to 10 mg, if the effect is not sufficient. When the doctor decides to stop the treatment, he will gradually decrease the dose to avoid withdrawal syndrome.
Ambien is available as oral pills, sublingual pills and oral sprays. Thus, it is easy and convenient to take it before bedtime. The control of the dosage must be strict to avoid adverse effects.
Ambien or Zolpidem is well-known and widely used in clinical practice. Only in the USA, there are millions of prescriptions for this medicine every year. However, as with other powerful medicines, one should be careful with it and strictly follow the recommendations of the doctor on the intake, duration of the treatment and dosage.
In addition to medical treatment, sleep disorders should be cured by introducing sleep hygiene and behavioral therapy in the everyday life of the patient. Such a combination is the most powerful and allows us to achieve sustainable results and improve sleep quality once and for all.