Ativan: Indications, Administration and Drug Interactions

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Ativan Medication Review

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Welcome to this useful review of Ativan medication. Ativan, likewise known by its generic name lorazepam, is a broadly prescribed medication primarily utilized to manage anxiety and related conditions. This article covers key aspects of Ativan, including its indications, administration, and important drug interactions for individuals considering or currently taking this medication.

Whether you are a healthcare professional striving to expand your knowledge or a patient exploring treatment options, this Ativan drug review is directed to grant you valuable information to make informed decisions about this medication.


Ativan (Lorazepam) is a benzodiazepine medication that was developed by DJ Richards. It was launched on the market in the United States in 1977. FDA-approved indications include short-term relief of anxiety symptoms related to anxiety disorders, anxiety-associated insomnia, anesthesia premedication in adults to facilitate anxiety or to produce sedation/amnesia, and management of status epilepticus. In addition, off-label (non-FDA-approved) indications are fast tranquilization of the agitated patient, alcohol withdrawal syndrome, insomnia, panic disorder, vertigo, and others.


Ativan (Lorazepam) may be administered orally (0.5 mg tablet, 1 mg tablet, 2 mg tablet, oral concentrate solution 2 mg/mL, 1 mg extended-release capsule, 2 mg extended-release capsule, and 3 mg extended-release capsule). Moreover, Ativan may be administered via intravenous(IV) or intramuscular(IM) injection (2 mg/mL solution and 4 mg/mL solution). The dosage and frequency of administration may vary depending on the patient’s age, condition, and response to treatment.

Drug Interactions

Ativan is undoubtedly a helpful medication utilized to treat anxiety and related conditions. However, it may interact with other drugs as well as alcohol and central nervous system depressants, potentially causing drowsiness and respiratory depression. Consult a healthcare professional to estimate potential drug interactions and ensure safe and effective use of Ativan.


Ativan medication may interact with certain foods. Avoid alcohol consumption since it may enhance Ativan’s sedative effects. Moreover, grapefruit and its juice may interfere with the drug’s metabolism, potentially resulting in increased side effects. It is of decisive importance to consult a healthcare professional for guidance on dietary restrictions while taking Ativan.

Medical Contraindications

Ativan, or lorazepam, is a popular medication usually prescribed for anxiety and some seizure disorders. Nevertheless, it is important to be aware of its medical contraindications. Ativan should not be employed in individuals with a history of allergic reactions to benzodiazepines or related drugs. It is likewise contraindicated in individuals with severe respiratory insufficiency, acute narrow-angle glaucoma, or a history of substance abuse.

In addition, caution is recommended when taking Ativan in pregnant or nursing women since it may have adverse effects on the developing fetus or breastfeeding infant. Moreover, as was mentioned above, combining Ativan with alcohol or other central nervous system depressants may be dangerous and strongly discouraged. Always consult your doctor before utilizing Ativan to make sure it is safe and appropriate for your concrete medical condition.

Important Considerations

Individuals who are thinking about starting to take Ativan should be aware of important considerations. For instance, Ativan should be employed cautiously since it may be habit-forming and result in dependency.

Although Ativan is an effective medication, it may still trigger definite side effects. Some of the most common adverse effects associated with this medication include drowsiness, tiredness, unsteadiness, nausea, restlessness or excitement, blurred vision, dizziness, weakness, diarrhea, changes in appetite, constipation, changes in sex drive or ability, and others.

Unfortunately, some side effects may be serious. If you experience such symptoms as shuffling walk, trouble talking, yellowing of skin or eyes, persistent tremor or inability to sit still, rash, hives, itching, swelling of the face, eyes, or mouth, wheezing, or shortness of breath, and irregular heartbeat, call your healthcare provider or ask for emergency medical treatment.


To conclude, Ativan is a medication that may grant effective relief for individuals struggling with anxiety and some other conditions. Its rapidly-acting nature and ability to facilitate symptoms make it a valuable instrument in the treatment of anxiety disorders. Nevertheless, it is crucial to utilize Ativan under the guidance of a qualified healthcare professional and weigh the benefits and disadvantages since it carries the risk of dependency and side effects.